Butabarbital decreases results of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep track of Closely. Coadministration of CYP3A4 inducers may possibly lessen sufentanil levels and efficacy, perhaps precipitating withdrawal syndrome in clients who've produced Actual physical dependence to sufentanil. Discontinuation of concomitantly used CYP3A4... https://rufusm186qtv6.theobloggers.com/profile