There exists a release of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors within the dorsal horn to lower afferent pain transmission and produce analgesia. Thus, medications like clonidine that focus on alpha-two receptors can affect the transmission of ache. Applies to clonidine: oral tablet, oral https://ericy950qgw5.tdlwiki.com/user