PKA phosphorylates Myosin Binding Protein-C (MyBP-C) and troponin I (TnI) inside the cardiac myofibril. TnI is the inhibitory element in the trimeric troponin molecule that makes up the Ca2+-switch of the contractile apparatus. TnI binds to TnC when Ca2+ is certain to TnC, while in the absence of Ca2+, the https://bempedoicacid09875.blogozz.com/27635084/the-ultimate-guide-to-werner-syndrome-recq-helicase-in-1